American Express cardholders have access to a special collection of Amex Offers, which you can find published at the bottom of your online account profile. Each American Express card you carry may be eligible for the same offer so you can save multiple times, but sometimes the offers do vary.
Two significant Amex Offers that were just announced today allow you to save $15 off Amazon.com (when you spend $60) and $10 off Uber (when you spend $20). I only found these on my Amex Platinum and Premier Rewards Gold cards, not the SPG cards, so they appear not to be as widely available as other offers.
I’ve also seen some new promotions for Regal Cinemas, which may be useful to those of you planning a trip to the movies over the holidays, and customized greeting cards from Minted.
In general these offers add up over the course of a year to save me more than the cost of the annual fee. Amex does have high annual fees on some of its cards, but the benefits are great and include things like free lounge access or airline fee credits. Anything you can do to earn statement credits and bring down the annual cost of carrying this cards is a good deal.